Modeling Podocyte Ontogeny and Podocytopathies with the Zebrafish

Modeling Podocyte Ontogeny and Podocytopathies with the Zebrafish

Blog Article

Podocytes are exquisitely fashioned kidney cells that serve an essential role in the process of blood filtration.Congenital malformation or damage olea europaea montra to podocytes has dire consequences and initiates a cascade of pathological changes leading to renal disease states known as podocytopathies.In addition, animal models have been integral to discovering the molecular pathways that direct the development of podocytes.In this review, we explore how researchers have used the zebrafish to here illuminate new insights about the processes of podocyte ontogeny, model podocytopathies, and create opportunities to discover future therapies.